Laboratory of Neurochemistry and Behavior
The Neurochemistry and Behaviour research unit is involved in metabolic-neurochemical and behavioural research and clinical neurological diagnostic and therapeutic investigations. The main mission of the research group consists of the development of diagnostic and/or therapeutic measures for neurological diseases and the clarification of the underlying pathophysiological processes. Biochemical, neurochemical, behavioural, electrophysiological, neuroimaging, clinical and animal pharmacological and epidemiological research is performed. The group has special interest in ethical considerations. The main fields of research can be summarized as follows:
- Evaluation of amino acids and amino acid analogues as candidate uremic toxins.
- Behavioural and neurochemical validation of models for cognitive retardation and deterioration. Behavioural observations include baseline and age-dependent assessment of neuromotor and cognitive abilities, and assessment of the efficacy of therapeutic interventions (incl. gene rescue and stem cell techniques).
- Clinical and diagnostic research. The research group has experience in diagnostic procedures involving neurochemical, electrophysiological and neuroimaging (mainly SPECT) and neurocognitive parameters.
- Analysis of markers for neurodegenerative conditions (a.o. dementia): neurochemical, genetic, neuropathological, etc.
- Epidemiological research, cross-sectional and prospective on large cohorts healthy populations and patient groups (a.o. dementia)
| Head: Prof. Dr. P.P. De Deyn, MD, PhD |
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| Laboratory of Neurochemistry and Behavior University of Antwerp Campus Drie Eiken Universiteitsplein 1 BE-2610 Antwerpen |
| Tel: +32 3 265 26 20 Fax: +32 3 265 26 18 |
| mail prof. De Deyn |
Reference Center for Biological Markers of Memory Disorders
The Rodent Behavioural Research Unit
Phd-defences
2011-07-04
Neuropeptides and animal modeling: from pathophysiological mechanisms to therapeutic applications
Annemie Van Dijck
Promotor: Prof. dr. Peter P. De Deyn
2011-06-06
Genotype-phenotype correlations in hereditary neuropathies: a systematic approach
Jonathan Baets
Promotors:Prof. Dr. Peter De Jonghe, Prof. Dr. Vincent Timmerman
2011-06-01
Cerebellar processing of tactile input
Koen Tahon
Promotor: Prof. Dr. Erik De Schutter
2011-05-17
Characterization and validation of cerebrospinal fluid biomarkers in dementia and mild cognitive impairment
Nathalie Le Bastard
Promotors: Prof. dr. Peter P. De Deyn and Prof. Dr. S. Engelborghs
2011-01-27
Secondary edema in patients with stroke: Actigraphic and volumetric evaluation.
Nick Gebruers
Promotors: Prof. dr. P. P. De Deyn, Prof. dr. S. Engelborghs and Prof. dr. S. Truijen.
2010-12-21
Molecular Genetics and Biology of Intermediate Charcot-Marie-Tooth neuropathy
Gonçalves Ricardo
Promotors: Prof. Dr. V. Timmerman & A. Jordanova
2010-12-08
Molecular genetic analysis of genes for inherited axonal peripheral neuropathies
Rotthier Annelies
Promotor: Prof. Dr. V. Timmerman
2010-12-07
Elucidation of the role of progranulin (PGRN) in frontotemporal dementia (FTD) with mouse models
Wils Hans
Promotors: Prof. C. Van Broeckhoven & Prof. S. Kumar-Singh
2010-11-23
Additional Value of Quantitative EEG in Ischemic Stroke
Rishi V. A. Sheorajpanday
Promotor: Prof. dr. Peter P. De Deyn
Co-promotor: Prof. Dr. G. Nagels
2010-10-21
Molecular genetic analysis of Alzheimer dementia
Bettens Karolien
Promotors: Prof. C. Van Broeckhvoen & K. Sleegers
2010-02-02
The predictive value of biochemical parameters among which amino acids and amino acid analogues in acute ischemic stroke
Raf Brouns
Promotor: Prof. dr. Peter P. De Deyn
Co-promotor: Prof. Dr. Bart Marescau
pictures
2009-12-14
Identification of novel genetic factors for Parkinson´s disease
Nuytemans Karen
Promotor: Prof. C. Van Broeckhoven
Co-promotor: Jessie Theuns
2009-05-19
Novel insights and broadening of the phenotypic spectrum for epilepsy caused by mutations in the SCN1A and SLC2A1 genes
Suls Arvid
Promotor: Prof. Dr. P. De Jonghe
2009-03-20
Molecular mechanisms of extracellular and intracellular proteinopathy in Alzheimer´s disease and frontotemporal dementia
Pirici Daniel
Promotors: Prof. S. Kumar-Singh, Prof. C. Van Broeckhoven
2008-12-15
Molecular genetic analysis of Alzheimer disease
Brouwers Nathalie
Promotor: Prof. C. Van Broeckhoven
2008-09-08
Molecular genomics of tau-negative, ubiquitin-positive frontotemporal lobar degeneration
Gijselinck Ilse
Promotors: Prof. C. Van Broeckhoven, M. Cruts
2008-04-21
Loss-of-function mechanisms and intraneuronal Aβ in cellular and mouse models of Alzheimer disease.
Van Broeck Bianca
Promotors: Prof. S. Kumar-Singh, Prof. C. Van Broeckhoven
2007-10-08
Neuropsychological and neurophysiological aspects of cognition in multiple sclerosis
Guy Nagels
Promotor: Prof. dr. Peter P. De Deyn
pictures
2007-09-21
The APP23 model as a model of human behavioural and psychiatric disturbances associated with dementia
Ellen Vloeberghs
Promotor: Prof. dr. Peter P. De Deyn
Co-promotor: Dr. Debby Van Dam
pictures